Cystic+Fibrosis

= AC_Voki_Embed(200,267,"fb053067412653377dbbe04a151aed67",360000, 1, "", 0); Get a Voki now!= =No Answers, No Cure: Cystic Fibrosis= media type="youtube" key="90_ovR1AHrg&hl=en" height="355" width="425" This video shows a kid who has Cystic fibrosis. This video basically tries to send the message out to people saying that these kinds of people need help and support.

Cystic fibrosis (CF) is known as a clinical syndrome characterized by chronic sinopulmonary infection as well as by gastrointestinal, nutritional, and other abnormalities. The genetic basis for CF is a well-characterized, severe monogenic recessive disorder. About 80-95% of patients with CF would have respiratory failure brought on by chronic bacterial infection and concomitant airway inflammation. The patients lungs are often colonized or infected in infancy and early childhood with organisms such as //Staphylococcus aureus// and //Haemophilus influenzae//, that could damage the epithelial surfaces, leading to increased attachment of, and eventual replacement by, //P. aeruginosa//. For more information, click [|here]. It is the most common lethal autosomal-recessive disease in the Caucasian population. It causes obstruction and bacterial accumulation in the digestive, respiratory, and reproductive tracts and abnormal sweat chloride levels. CF results from the mutation of CFTR protein gene (Cystic Fibrosis Transmembrane Regulator), which help regulate salt and water excretion in exocrine cells. For more information, click [|here].

Symptoms from cystic fibrosis: 1) For newborns: 2) Children and young adults Cystic fibrosis may also be accompanied by: All symptoms listed here was found on the following site: click [|here].
 * Failure to grow
 * Bulky and greasy stools (steatorrhea)
 * Frequent respiratory infections
 * Salty taste to the skin. People with CF would usually have higher than normal amounts of salt (sodium chloride) in their sweat. This may be one of the first signs parents notice because they can taste the salt when they kiss their child.
 * Blockage in the bowels
 * Foul-smelling, greasy stools
 * Delayed growth
 * Thick sputum (It's easy for parents to overlook this sign because young children tend to swallow their sputum rather than cough it up)
 * Coughing or wheezing
 * Frequent chest and sinus infections with recurring pneumonia or bronchitis
 * Protrusion of part of the rectum through the anus (rectal prolapse) (this is often caused by stools that are difficult to pass or by frequent coughing)
 * Enlargement or rounding (clubbing) of the fingertips and toes (although clubbing eventually occurs in most people with CF, it also occurs in some people born with heart disease and other types of lung problems)
 * Growths (polyps) in the nasal passages
 * Cirrhosis of the liver due to inflammation or obstruction of the bile ducts
 * Displacement of one part of the intestine into another part of the intestine (intussusception) in children older than age 4

CF is an inherited or genetic condition. In order to develop the condition you need to inherit two cystic fibrosis genes, one from your mother and one from your father. If you inherit only one cystic fibrosis gene, you are called a carrier and do not have symptoms.

Illustration showing how cystic fibrosis is inherited When both parents are carriers, with each pregnancy there is a: 1 in 4 chance of having a child with cystic fibrosis 1 in 2 chance of having a child who is a carrier 1 in 4 chance of having an unaffected child All info here was retrieved from [|this site]

Solutions and/or therapies that are available for cystic fibrosis: Currently, there are no cures for CF, but research is under way through gene therapy. Current treatments aim to control the symptoms and have two main goals: Physiotherapy If you have CF you will need daily chest physiotherapy, which involves vigorous massage to help loosen the sticky mucus.
 * to improve nutrition by providing supplements containing enzymes to help digestion
 * to reduce chest infections with frequent physiotherapy and either occasional or continuous antibiotics

Enzyme therapy With each meal or snack, most people with cystic fibrosis need to take replacement enzymes such as pancreatin (eg Pancrex). These supply the missing pancreatic enzymes and allow proper digestion. People with cystic fibrosis normally need vitamin and mineral supplements as well. Vaccinations for CF: The usual childhood vaccinations, like measles, mumps and rubella (MMR) and diphtheria, tetanus and whooping cough (DTP) are important for children with cystic fibrosis. If you have cystic fibrosis you should also be vaccinated against flu and pneumococcus to help prevent chest infections. For more information about vaccines, please see the separate BUPA fact sheets, [|Childhood immunization] and [|Colds and flu]. All info on solutions and therapies on this site was from the [|following site].

The most common chromosome abnormality associated with male infertility is Klinefelter syndrome, in which males carry an extra X chromosome (47,XXY). Klinefelter syndrome is characterized by an increased chance for learning disabilities, minor physical differences, and infertility. Most men with Klinefelter syndrome go undetected until experiencing difficulty with their partner concerning children, and an evaluation for infertility is performed. With the assistance of ICSI, men with Klinefelter syndrome are often able to have children. Although these men can have healthy children, there is also an increased chance to have a child with a sex chromosome abnormality. For more information, click [|here].